The scientific study of the effects of building design on psychological function and dysfunction is in its infancy, though, historically, any right-thinking architect will have considered the likely effects of design whilst formulating their plans. Considering the writings of Nikolaus Pevsner to the findings of modern neuroscience we will try to explain how and why buildings may influence our behaviour? How might space, form, function, light and colour affect cognition and mental state? Why do the exteriors and interiors of buildings conjure a range of emotions in different people? And what explanations exist to account for 'sick building syndrome'? In this lecture, expect to be dazzled by images of beautiful architecture and to explore the relationship between art and cutting-edge science.